周明扬
副教授、硕士生导师
联系方式：18764437337，myzhou@qlu.edu.cn
办公室、实验室：化工楼C517
学习及工作经历
2016.10 至今 56net亚洲必嬴 副教授
2016.10-2017.9 美国 University of Oklahoma 访问学者
2014.1-2016.9 56net亚洲必嬴 讲师
2008.9-2013.7 山东大学微生物技术国家重点实验室 博士
2004.9-2008.6 山东大学生命科学学院 本科
研究方向
目前主要研究特殊环境天然产物、酶催化和电催化，包括：南极土壤来源的微生物分泌的抗耐药菌等生物活性次级代谢产物及酯酶/脂肪酶、蛋白酶的性质和应用，P450酶结合电催化在化学合成中的应用，主持国家自然科学基金青年项目、山东省自然科学基金面上项目、山东省科技发展计划、56net亚洲必嬴（山东省科学院）培优项目、青年博士联合基金等项目。
主要论文：
1 Liu XY, Zhou MY*, Sun R, Xing S, Wu T, He HL, Chen JB, and Bielicki JK. Characterization of a novel esterase Est33 from an Antarctic bacterium: a representative of a new esterase family. Front Microbiol. 2022, 13:855658
2 Liu JM, Liu WJ, Xing S., Zhou MY*, Zhang YC, Xia XK, and Wu HK. Bioactive compounds from the Antarctic bacterium Pseudomonas sp. A6-5. Chemistry of Natural Compounds. 2022, 58:371-373.
3 Liu XY, Zhou MY*, Xing SH, Wu T, He HL, Bielicki JK, Chen JB.. Identification and biochemical characterization of a novel hormone-sensitive lipase family esterase Est19 from the Antarctic bacterium Pseudomonas sp. E2-15. Biomolecules. 2021, 11:1552
4 Liu JM, Liu WJ, Xing SH, Zhang XY, He HL, Chen JB, Bielicki JK, Zhou MY*. Diversity of protease-producing bacteria in the soils of the South Shetland Islands, Antarctica. Antonie Van Leeuwenhoek. 2021, 114: 457–464.
5 Shao DX, Wu YW, Hu SC, Gao W, Du YL, Jia XF, Liu SY*, Zhou MY*, and Chen JB*, Decoupled photoelectrochemical cerium-catalyzed oxydichlorination of alkynes: slow releasing of chloride ions and chlorine radicals, ACS Sustainable Chem. Eng. 2022, 10:10294−10302.
6 Sun R, Wu T, Xing SH*, Wei SH, Bielicki JK., Pan XF, Zhou MY, Chen JB*. Caffeic acid protects against atherosclerotic lesions and cognitive decline in ApoE/ mice, Journal of Pharmacological Sciences, 2023, 151:110-118.
7 Wang AH, Liu X, Gao W, Ma L, Liu SY, Zhang GF, Zhou MY, Jia XF and Chen JB*, Cathode enabled high faradaic efficiency: reduction of imines to amines with H2O as a H-source, Chem. Commun., 2022, 58:9906
8 Wang K, Liu XY, Yang SY, Tian Y, Zhou MY, Zhou JH, Jia XF, Li BY*, Liu SY*, and Chen JB*. In situ alkyl radical recycling driven decoupled electrophoto-chemical deamination, Organic Letters.2022,24:3471-3476
9 Wu YW, Xu SH, Wang H, Shao DX, Qi QQ, Lu Y, Ma L, Zhou JH, Hu W, Gao W*, and Chen JB*, Directing group enables electrochemical selectively metabromination of pyridines under mild conditions, J. Org. Chem. 2021, 86:16144-16150.
10 Lv SD, Han XX, Wang JY, Zhou MY, Wu YW, Ma L, Niu LW, Gao W, Zhou JH, Hu W, Cui YZ, and Chen JB*, Tunable electrochemical C-N versus N-N bond formation of nitrogen-centered radicals enabled by dehydrogenative dearomatization: biological applications, Angew. Chem. Int. Ed. 2020, 59:11583-11590
11 Zhou MY*, Zhang YJ, Zhang, XY, Yang, XD, He HL, Ning DL, Du ZJ. Flavobacterium phocarum sp. nov., isolated from soils of a seal habitat in Antarctica. Int J Syst Evol Microbiol. 2018, 68:536-541.
12 Zhou MY*, Zhang XY, Yang XD, Zhang YJ, He HL, Ning DL. Flavobacterium ardleyense sp. nov., isolated from Antarctic soil. Int J Syst Evol Microbiol. 2017, 67:1016-1022.
13 Zhou, MY, Wang, GL, Li, D, Zhao, DL, Qin, QL, Chen, XL et al. Diversity of both the cultivable protease-producing bacteria and bacterial extracellular proteases in the coastal sediments of King George Island, Antarctica. 2013, PLoS One 8.
14 Zhou MY, Chen XL, Zhao HL, Dang HY, Luan XW, Zhang XY et al. Diversity of both the cultivable protease-producing bacteria and their extracellular proteases in the sediments of the South China sea. Microb Ecol. 2009, 58:582-590.
15 Li Y, Zhou MY, Wang FQ, Wang ET, Du ZJ, Wu CY, Zhang ZP, Liu W, Xie ZH, Photobacterium proteolyticum sp. nov., a protease-producing bacterium isolated from ocean sediments of Laizhou Bay. Int J Syst Evol Microbiol. 2017, 67:1835-1840.
16 Li Y, Wu CY,Zhou MY, Wang ET, Zhang ZP, Liu WN, ZP, Liu W, Ning JC, Xie ZH, Diversity of Cultivable Protease-Producing Bacteria in Laizhou Bay Sediments, Bohai Sea, China. Front Microbiol. 2017, 8:405
17 Zhao GY, Zhou MY, Zhao HL, Chen XL, Xie BB, Zhang XY et al. Tenderization effect of cold-adapted collagenolytic protease MCP-01 on beef meat at low temperature and its mechanism. Food Chem. 2012, 134:1738-1744.
18 Ran LY, Su HN, Zhou MY, Wang L, Chen XL, Xie BB et al. Characterization of a novel subtilisin-like protease myroicolsin from deep sea bacterium Myroides profundi D25 and molecular insight into its collagenolytic mechanism. J Biol Chem. 2014, 289:6041-6053
19 Zhao HL, Chen XL, Xie BB, Zhou MY, Gao X, Zhang XY et al.. Elastolytic mechanism of a novel M23 metalloprotease pseudoalterin from deep-sea Pseudoalteromonas sp. CF6-2. J Biol Chem. 2012, 287, 39710-39720.
20 Li HJ, Zhang XY, Zhang YJ, Zhou MY, Gao ZM, Chen XL et al. Rheinheimera nanhaiensissp. nov., isolated from marine sediments, and emended description of the genus Rheinheimera Brettar et al. 2002 emend. Merchant et al.2007. Int J Syst Evol Microbiol. 2011, 61:1016-1022
21 Zhang YJ, Zhang XY, Zhao HL, Zhou MY, Li HJ, Gao ZM et al. Idiomarina maris sp. nov., a marine bacterium isolated from sediment of the South China Sea. Int J Syst Evol Microbiol. 2012, 62:370-375.
授权专利：
1周明扬，刘晓雨，邢澍，刘文杰，刘健敏，武涛，吴汉夔，一种具有降解手性酯活性的酯酶及其编码基因和应用，ZL201911377891.1
2周明扬，刘文杰，邢澍，刘晓雨，武涛，刘健敏，吴汉夔；一种酯酶、编码基因、载体、重组细胞及其应用，ZL201911398522.0
3周明扬，刘健敏，邢澍，刘文杰，刘晓雨，武涛，吴汉夔，一种酯酶及其编码基因和应用，ZL201911396295.8
4周明扬，武涛，邢澍，刘晓雨，刘健敏，刘文杰，吴汉夔，一种南极土壤来源的酯酶及其编码基因和应用，ZL201911398502.3
5 张玉忠，赵慧琳，陈秀兰，周明扬，解彬彬，张熙颖，周百成，一种深海弹性蛋白酶基因及其制备方法与应用，ZL201010246786.7
6 张玉忠，冉丽媛，陈秀兰，周明扬，张熙颖，何海伦，石梅，解彬彬，周百成，一种深海嗜冷耐盐胶原蛋白酶及其编码基因myr02与应用，ZL201110048859.6
7 张玉忠，赵国琰，陈秀兰，周明扬，张熙颖，何海伦，解彬彬，石梅，周百成，适冷蛋白酶MCP-01在肉类嫩化中的应用，ZL201110121380.0
